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Insulin Date Written 2007
Author Joe Holmes Date Revised  

Insulin kills: One of the leading cause of deaths by insulin is higer doses than needed.

1. "On the day in question, a resident physician wrote an order for four units of slow-release insulin. A nurse misinterpreted the order and gave the patient forty units of slow-release insulin. As it was slow-release insulin, it took nearly a day for the patient to go into insulin shock. The treating physician recognized signs of insulin shock during morning rounds the next day. The physician moved the patient to the ICU, but, after consulting with the family, ordered that no extraordinary measures be taken to revive the patient, and the patient died."  Eagle Eye Newsletter

2. "AN INQUEST into the death of a diabetic has focused attention in Britain on treatment with insulin derived from human rather than animal sources. Diabetes specialists, the British Diabetic Association and patients are becoming concerned at the apparent increase in deaths from hypoglycaemia, or low blood sugar. The increase may be related to the modern policy of monitoring blood sugar closely with the idea of keeping it as low as a patient's lifestyle can tolerate. Some researchers also believe that patients who have switched to human insulins run a greater risk of hypoglycaemia."  New Scientist

3. "CHICAGO - Insulin pumps are used by tens of thousands of teenagers worldwide with Type 1 diabetes, but they can be risky and have been linked to injuries and even deaths, a review by federal regulators finds."   Yahoo News    FOX News

4. "The deaths of two elderly patients in Chicago hospital have prompted a police investigation. The two died from an insulin overdose and one other remains in a coma and authorities suspect they may have deliberately been given an overdose of insulin. Officials at the Chicago Medical Center were called in after the three patients appeared to have received unusually high amounts of insulin. The Chicago Police Department says the investigation is in the early stages and as yet they do not know if there was criminal intent. The hospital says whether it was a medical error, a question of product integrity or defective test results, is at present unclear. It appears that all of the patients were elderly women, being treated in the same wing of the hospital; they were not diabetic and had not been prescribed insulin."   News     CBS 2 Chicago

5. "In the recent study of UCLA researchers, they found out that the mortality rate of seniors who die of advanced heart failure with diabetes and treated with insulin is four times higher than that of heart failure patients with diabetes treated with oral medications."    Senior's Blog

6. " Waukesha - A judge has refused to dismiss a lawsuit seeking damages from Waukesha County Technical College in the death of a diabetic woman who was treated by a college nursing student...Sauer's family contends that she was administered 20 times the normal dose of insulin."   JSOnline

7. "Fonarow's team followed a group of 554 patients with advanced heart failure, of whom 132 had diabetes. Of these, about a third were on insulin therapy while the rest used other, oral medications or diet restrictions to control blood sugar levels. One-year survival rates were 90 percent for non-diabetic patients, 86 percent for non-insulin-treated diabetic patients, but only 62 percent for insulin-treated diabetic patients, the investigators report in the American Heart Journal."In the near term,... Fonarow concluded, "clinicians need to recognize that heart failure patients with diabetes who are treated with insulin are at particularly high risk for mortality and deserve increased attention."   Virtual Medical Center

8. "Alarming rise in diabetic Death Rates reported by the counters, Center for Disease Control

* 1980 - 1996 Diabetes was the 7th leading cause of death (cod).2
* 2000-2002 Diabetes was the 6th leading cod 2
* 2003 Diabetes was the 5th leading cod 1

The synthetic type of insulins combined with medical advice, based on the American Diabetic Association?s (ADA?s) now status quo Diabetic Complication Control Trial?s (DCCT?s) guidance has caused the condition of many diabetics to continue to worsen. In 1983 animal insulins began being replaced by synthetic human type insulin (cloned from e-coli or yeast). The last of the animal insulins in the United States was Iletin 1 (85% beef & 15% pork)Since 1998, no form of beef insulin has been manufactured in the United States.Note: Beef Insulin sales began in 1921 and to date has been the only insulin made offering a true 24 hour basal action for most healthy diabetics, with one shot a day.Synthetic Insulin sales began in 1983. The synthetics claim to offer 24 hour action. This is neither accurate nor possible for insulin dependent diabetics (idd)."    Diabetic Type

9. "Wal-Mart Stores Inc. has settled out-of-court a wrongful death lawsuit brought by the family of a man killed by an insulin overdose. The man, Keith Scofield, died in January 2006 after receiving a dose of insulin that was far too strong for him. Scofield normally used a low-strength insulin to treat his Type 2 diabetes. In December 2005, staff at a Virginia Wal-Mart mistakenly gave him Humulin R (u-500), rather than the Humulin R (u-100) that he had apparently requested. Scofield did not realize he had been given the wrong dose. He went ahead and injected himself with the medication, then fell into a coma. Sadly, he died twelve days later."   Medicine Watch

10. "Among 10,000-plus participants in the ACCORD trial, early analysis showed that 257 participants receiving intensive insulin therapy for type 2 diabetes with a target A1C level less than 6 percent had died since the beginning of the trial — compared with 203 participants receiving standard treatment with a target A1C level between 7 percent and 7.9 percent. About half the excess deaths were related to heart disease. Due to the possible risks, in February 2008 researchers halted the part of the trial that required intensive insulin therapy."   Mayo Clinic

11.Department of Biochemistry, Istanbul Faculty of Medicine, Istanbul University: Type 2 diabetes is related to the hormone Resistin and when its levels increase insilin is less effective and when insilin increases Resistin increases.
PMID: 18188531

12.Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, Vidal H, Rieusset J. Université Lyon 1, Lyon, France. Mitochondrial dysfunction in skeletal muscle has been implicated in the development of type 2 diabetes. Mice fed a high sucrose diet showed no mitochondrial dysfunction in one month, however in an extended period they developed mitochondrial dysfunction. Antioxidant treatment blocked the mitochondrial dysfunction. PMID: 18188455

13.García-Fernández M, Delgado G, Puche JE, González-Barón S, de Cortázar IC.Department of Physiology, School of Medicine, University of Málaga, Málaga, Spain; Department of Medical Physiology, School of Medicine, University CEU-USP, Madrid, Spain. Growth Hormone (GH) and Insulin-like Growth Factor I (IGF-I) concentrations decline with age...IGF-I therapy was able to revert insulin resistance and to reduce cholesterol and triglycerides levels increasing significantly free fatty acid concentrations. Old rats showed higher oxidative damage in brain and liver tissues associated with alterations in antioxidant enzyme activities. IGF-I therapy reduced oxidative damage in brain and liver, normalizing antioxidant enzyme activities and mitochondrial dysfunction. In conclusion, low doses of IGF-I restore circulating IGF-I, improve glucose and lipid metabolism, increase testosterone levels and serum total antioxidant capability and reduce oxidative damage in brain and liver associated with a normalization of antioxidant enzyme activities and mitochondrial function. PMID: 18187555

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