derived from glucocorticoid (steroid
hormone) produced by the adrenal glands.
See how emotions
affect the adrenal glands.
High Cortisol may cause chronic fatigue, sleepiness,
mood changes, inability to lose weight, diabetes, depression,
sex hormone changes and inability to cope with stress.
Cortisol increases and DHEA decreases as we age.
The pharm cure for high cortisol are MAOI drugs, numerous
physicians are reporting they harm the mind and body
and can even cause manic episodes for some with Bi
|Items listed in the scientific
reports below are reported to lower Cortisol.
Mao english name is Golden eye grass rhizone.
Huffington Post "Cortisol is a stress hormone designed
to give us the bursts of energy needed to escape a dangerous
situation, like running away from a tiger. Unfortunately,
modern life often convinces our brains that everything
is a stressful situation -- and it's nearly impossible
to escape an overflowing inbox. Instead of resolving
the issue, we stay on high alert all the time, with
elevated blood pressure and glucose levels. Over time,
this becomes a serious health issue, despite how conventional
medicine neglects the importance of this bad-boy hormone
-- and that's not just my opinion, but the evidence
continues to mount." http://www.huffingtonpost.com/sara-gottfried-md/cortisol_b_2822176.html
Elevated cortisol levels can affect energy, stress,
thyroid, adrenal glands increasing anxiousness irritability
and stress, weight gain, bone loss, contribute to diabetes
and heart disease risk.
Cortisol is known as the aging hormone. High cortisol
causes a “fight or flight” response which
stimulates your sympathetic nervous system and adrenal
glands resulting in a decrease of digestive secretions
and a increase in blood pressure.
The scientific formula to lower cortisol is to inhibit
the activity of monoamine oxidase
in the hypothalamus.
inhibitors (MAOIs) are chemicals which inhibit the activity
of the monoamine oxidase enzyme family. They have a
long history of use as medications prescribed for the
treatment of depression. They are particularly effective
in treating atypical depression. They are also used
in the treatment of Parkinson's Disease and several
other disorders." http://en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor
Authors note: There are numerous reports that the pharmicutical
MAOI's have detremintal effects on the mind and body.
Below are research reports of natural things reported
to lower cortisol and monoamine oxidase.
enzymatic activity and CYP3A4 protein expression (high
cortisol) could be inhibited by Xian Mao."
Xian Mao english name is Golden
eye grass rhizone.
"...The data also
show, albeit to a lesser extent, inhibitory properties
of herbs originating from the mint family (Lamiaceae)
and Turmeric, Comfrey, Bringraj, Skullcap, Kava-kava,
Wild Indigo, Gentian and Green Tea. In conclusion, the
data reflect relative potency information by rank of
commonly used herbs and plants that contain
human MAO-B inhibitory properties in their
natural form. http://www.ncbi.nlm.nih.gov/pubmed/?term=inhibit+monoamine+oxidase+with+natural+herbs
This scientific research report
lists natural herbs that work as MAO inhibitors thus
these herbs work to reduce high Cortisol levels.
results indicate that daily supplementation with a combination
of Magnolia bark extract and Phellodendron bark extract
(Relora®) reduces cortisol exposure and perceived
daily stress, while improving a variety of mood state
parameters, including lower fatigue and higher vigor.
These results suggest an effective natural approach
to modulating the detrimental health effects of chronic
stress in moderately stressed adults. Future studies
should examine the possible performance and recovery
benefits of Relora supplementation in athletes overstressed
by the physical and psychological demands of training
and competition." http://www.ncbi.nlm.nih.gov/pubmed/23924268
Relora is a trade name of NOW
confirmed the antidepressant-like effect of magnolol,
which maybe primarily mediated by reversing the glial
atrophy in the UCMS rat brain. http://www.ncbi.nlm.nih.gov/pubmed/23632393
(Atrophy means damage or killing
of the glial cells in the brain, glial cells constitute
the majority of brain cells. What this is saying is
something doctors for ages claim can never happen, and
that is the restoration of brain cells. Imagine what
this could do for Parkisons, drug damage to the brain
of magnolia has been used in Oriental medicine to treat
a variety of remedies, including some neurological disorders.
Magnolol (Mag) and honokiol (Hon) are isomers of polyphenolic
compounds from the bark of Magnolia officinalis, and
have been identified as major active components exhibiting
anti-oxidative, anti-inflammatory, and neuroprotective
effects. In this study, we investigate the ability of
these isomers to suppress oxidative stress in neurons
stimulated by the ionotropic glutamate receptor agonist
N-methyl-D-aspartate (NMDA) and oxidative and inflammatory
responses in microglial cells activated by interferon-?
(IFN?) and lipopolysaccharide (LPS). We also attempt
to elucidate the mechanism and signaling pathways involved
in cytokine-induced production of reactive oxygen species
(ROS) in microglial cells... RESULTS:Exposure of Hon
and Mag (1-10 µM) to neurons for 24 h did not
alter neuronal viability, but both compounds (10 µM)
inhibited NMDA-stimulated superoxide production, a pathway
known to involve NADPH oxidase. In microglial cells,
Hon and Mag inhibited IFN?±LPS-induced iNOS expression,
NO, and ROS production. Studies with inhibitors and
immunocytochemical assay further demonstrated the important
role of IFN? activating the NADPH oxidase through the
p-ERK-dependent pathway. Hon and, to a lesser extent,
Mag inhibited IFN?-induced p-ERK1/2 and its downstream
pathway for ROS and NO production..." http://www.ncbi.nlm.nih.gov/pubmed/23356518
A report that agrees with report
5 that Magnolol reduces not only oxidative stress but
depression and mental issues.
administration resulted in a decrease in plasma cortisol
concentrations (mean, peak, and/or AUC) in healthy older
women and men. The cortisol-lowering effect of DHEA
was more pronounced in women than in men in our study..."
This report states that
DHEA lowers cortisol.