There two versions
one is mineral and the other is organic.
Some nutritional selenium are mineral; they are not
as good for the body as organic.
Selenomethionine, Sodium selenite and Semethylselenocysteine. Selenomethionine
has ability to deplete free radicals. https://en.wikipedia.org/wiki/Selenomethionine https://en.wikipedia.org/wiki/Sodium_selenite
is an essential ingredient for optimum health. Selenium
is essential to make Zinc work in the body and without
it Zinc may be ineffective. In other words you can have
sufficient zinc and you may not absorb it if you are
deficient in selenium. Zinc is an important mineral
in the body.
is important to recognize selenium comes in three forms;
When reading research about selenium check to see which
version they are testing.
much of the pharmaceutical or mineral form can be toxic.
||Toxic at 400 mcg.
||Tested therapeutic dose starts at 800 mcg. and tested
safe up to 1,200 mcg.
is found in foods such as Brazil nuts, walnuts, organ
meats, seafood, brewer's yeast, wheat germ and vegetables
such as broccoli, mushrooms, cabbage, onions and garlic.
If these foods are part of your diet, you can be assured
that you are not missing out on the benefits of selenium."
recent years, selenium has been shown to mediate a number
of insulin-like actions both in vivo and in
vitro...This review compares the action of
selenium to that of insulin and discusses the available
evidence in support of selenium as an insulin-mimetic.
trace element selenium (Se) is capable of exerting multiple
actions on endocrine systems by modifying the expression
of at least 30 selenoproteins, many of which have clearly
defined functions...These selenoenzymes are
capable of modifying cell function by acting as antioxidants
and modifying redox status and thyroid hormone metabolism.
Se is also involved in cell growth, apoptosis and
modifying the action of cell signalling systems and
transcription factors. During thyroid hormone synthesis
GPX1, GPX3 and TR1 are up-regulated, providing the thyrocytes
with considerable protection from peroxidative damage.
Thyroidal D1 in rats and both D1 and D2 in humans are
also up-regulated to increase the production of bioactive
3,5,3'-tri-iodothyronine (T3). In the basal state, GPX3
is secreted into the follicular lumen where it may down-regulate
thyroid hormone synthesis by decreasing hydrogen
in the diabetic rat, Se not only restores glycaemic
control but it also prevents or alleviates the adverse
effects that diabetes has on cardiac, renal and platelet
an essential biological trace element, is an integral
component of several enzymes, and its use as a nutritional
supplement has been popularized recently due to its
potential role in low concentrations as an antioxidant
and in higher concentrations as an anticancer agent.
Selenium has also been reported to act as an
insulin-mimetic agent with regard to normalization of
blood glucose levels and regulation of some
insulin-mediated metabolic processes...Our
results therefore show that selenium not only increased
the phosphorylation of proteins identified in the insulin
signal cascade but also affected the overall phosphorylation
state of the cell." http://www.ncbi.nlm.nih.gov/pubmed?term=9060997
Selenium, Manganese Superoxide Dismutase, and Intermediate-
or High-Risk Prostate Cancer... CONCLUSION:
These data suggest that the relationship between circulating
selenium levels at diagnosis and prognostic risk of
prostate cancer is modified by SOD2 genotype and indicate
caution against broad use of selenium supplementation
for men with prostate cancer."