The purpose of this site is to collect lab research by medical doctors about herbs that are proven to treat illnesses and counter the false attacks on herbs by the medical industry and false claims by alternative medicine. I let the science tell the facts.
index sitemap advanced
search engine by freefind

Irritable bowel syndrome (IBS

Some believe that proper functioning bowels is the key to health. The flora in the bowles may be the biggest contributor to a healthy immune system. Thus proper functioning bowels may be the gateway to good health. Ralated to Crohn’s & Colitis.

Two causes seldom listed are heavy metals, and parasites.

1. Wikipedia "Irritable bowel syndrome (IBS, or spastic colon) is a symptom-based diagnosis characterized by chronic abdominal pain, discomfort, bloating,and alteration of bowel habits. As a functional bowel disorder, IBS has no known organic cause.[1] Diarrhea or constipation may predominate, or they may alternate (classified as IBS-D, IBS-C or IBS-A, respectively). Historically a diagnosis of exclusion, a diagnosis of IBS can now be made on the basis of symptoms alone, in the absence of alarm features such as age of onset greater than 50 years, weight loss, gross hematochezia, systemic signs of infection or colitis, or family history of inflammatory bowel disease.[2][3] Onset of IBS is more likely to occur after an infection (post-infectious, IBS-PI), a stressful life event, or onset of maturity. Although there is no cure for IBS, there are treatments that attempt to relieve symptoms, including dietary adjustments, medication and psychological interventions. Patient education and a good doctor-patient relationship are also important.[4] Several conditions may present as IBS including coeliac disease, fructose malabsorption,[5] mild infections, parasitic infections like giardiasis,[6] several inflammatory bowel diseases, bile acid malabsorption, functional chronic constipation, and chronic functional abdominal pain. In IBS, routine clinical tests yield no abnormalities, although the bowels may be more sensitive to certain stimuli, such as balloon insufflation testing. The exact cause of IBS is unknown. The most common theory is that IBS is a disorder of the interaction between the brain and the gastrointestinal tract, although there may also be abnormalities in the gut flora or the immune system.[7][8] IBS has no effect on life expectancy. However, it is a source of chronic pain, fatigue, and other symptoms and contributes to work absenteeism.[9][10] The high prevalence of IBS[11][12][13] and significant effects on quality of life make IBS a disease with a high social cost.[14][15]"

2. National Digestive Diseases Information Clearinghouse (NDDIC)" The causes of IBS are not well understood. Researchers believe a combination of physical and mental health problems can lead to IBS. The possible causes of IBS include the following:

  • Brain-gut signal problems. Signals between the brain and nerves of the small and large intestines, also called the gut, control how the intestines work. Problems with brain-gut signals may cause IBS symptoms, such as changes in bowel habits and pain or discomfort.
  • GI motor problems. Normal motility, or movement, may not be present in the colon of a person who has IBS. Slow motility can lead to constipation and fast motility can lead to diarrhea. Spasms, or sudden strong muscle contractions that come and go, can cause abdominal pain. Some people with IBS also experience hyperreactivity, which is an excessive increase in contractions of the bowel in response to stress or eating.
  • Hypersensitivity. People with IBS have a lower pain threshold to stretching of the bowel caused by gas or stool compared with people who do not have IBS. The brain may process pain signals from the bowel differently in people with IBS.
  • Mental health problems. Mental health, or psychological, problems such as panic disorder, anxiety, depression, and post-traumatic stress disorder are common in people with IBS. The link between these disorders and development of IBS is unclear. GI disorders, including IBS, are often found in people who have reported past physical or sexual abuse. Researchers believe people who have been abused tend to express psychological stress through physical symptoms.
  • Bacterial gastroenteritis. Some people who have bacterial gastroenteritis—an infection or irritation of the stomach and intestines caused by bacteria—develop IBS. Researchers do not know why gastroenteritis leads to IBS in some people and not others, though psychological problems and abnormalities of the lining of the GI tract may be factors.
  • Small intestinal bacterial overgrowth (SIBO). Normally, few bacteria live in the small intestine. SIBO is an increase in the number of bacteria or a change in the type of bacteria in the small intestine. These bacteria can produce excess gas and may also cause diarrhea and weight loss. Some researchers believe that SIBO may lead to IBS, and some studies have shown antibiotics to be effective in treating IBS. However, the studies were weak and more research is needed to show a link between SIBO and IBS.
  • Body chemicals. People with IBS have altered levels of neurotransmitters, which are chemicals in the body that transmit nerve signals, and GI hormones, though the role these chemicals play in developing IBS is unclear. Younger women with IBS often have more symptoms during their menstrual periods. Post-menopausal women have fewer symptoms compared with women who are still menstruating. These findings suggest that reproductive hormones can worsen IBS problems.
  • Genetics. Whether IBS has a genetic cause, meaning it runs in families, is unclear. Studies have shown that IBS is more common in people with family members who have a history of GI problems. However, the cause could be environmental or the result of heightened awareness of GI symptoms.
  • Food sensitivity. Many people with IBS report that certain foods and beverages can cause symptoms, such as foods rich in carbohydrates, spicy or fatty foods, coffee, and alcohol. However, people with food sensitivity typically do not have clinical signs of food allergy. Researchers have proposed that symptoms may result from poor absorption of sugars or bile acids, which help break down fats and get rid of wastes in the body."

3. Everydayhealth "Abnormal serotonin levels. One dominant theory is that IBS is related to serotonin in the gut, says Steven Field, MD, a gastroenterologist and clinical assistant professor of medicine at New York University School of Medicine in New York City. You may have heard of serotonin as a chemical in your brain that helps to regulate your mood. But, actually, that work is only a fraction of its job. While a percentage of your body’s serotonin is found in your brain, it is also found in the walls of your colon. There, it may regulate bowel contractions and movements and secrete fluid, Dr. Fields says. Researchers have found that if you have an abnormal amount of serotonin in your gut or if the serotonin in your gut isn’t functioning the way it should, it can lead to IBS symptoms, Fields says. It could be why some people see an improvement in their IBS symptoms when they take antidepressants, many of which work by adjusting serotonin levels."

3. Pub Med "Polymorphisms in serotonin re-uptake transporter (SERT or SLC6A4) gene may play role in disturbance in gut function in irritable bowel syndrome (IBS)...CONCLUSION: The frequency of SLC6A4-polymorphism and higher levels of 5-HT were significantly associated with IBS, particularly in patients with diarrhea and abdominal pain, suggesting that SLC6A4 is a potential candidate gene involved in the pathogenesis (causes a disease) of IBS." Serotonin is common in antidepressant drugs and a common treatment for depression. This report states serotonin increases IBS and gut problems.




Recommended Information