The purpose of this site is to collect lab research by medical doctors about herbs that are proven to treat illnesses and counter the false attacks on herbs by the medical industry and false claims by alternative medicine. I let the science tell the facts.
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Gastroparesis, idiopathic

Gastroparesis is the condition of the stomach muscles not constricting at all or not constricting properly. (1)

Idiopathic is a medical term to indicate they do not know why or what is causing a disease or condition. (2)

The reports below suggest that three things may be related to this disease, diabetes, Ghrelin hormone, and oxidative stress. Items that may offer additional information of help with this disease are; oxidative stress, antioxidants, immune system,  MSG, Aspartame, Excito Toxins and Metabolic Mayhem.

1. "Gastroparesis is a stomach disorder in which food is digested more slowly than normal...With gastroparesis, however, the stomach muscles work poorly (or not at all), thus preventing the stomach from emptying properly...The most common causes of gastroparesis are: Idiopathic, Diabetes, either type 1 or type 2"

2. "Idiopathic is an adjective used primarily in medicine meaning arising spontaneously or from an obscure or unknown cause"

3. "...Women are more susceptible to gastroparesis than men...Researchers are now paying more attention to the possibility of using BH(4) as a therapeutic strategy in gastroparesis. The purpose of this review is to provide an overview of the regulation and function of nNOS by sex hormones and BH(4) and its potential role in the treatment of gastroparesis."

4. "...Here we review the evidence for the involvement of mast cells in the inflammation of the bowel wall caused by bowel manipulation that leads to motility disturbances such as postoperative gastroparesis and ileus. ...Further research on mast cell-related therapy either by stabilizing the mast cells or by blocking specific mast cell mediators as adjunctive therapy in IBD is encouraged, bearing in mind that several drugs currently used in the treatment of IBD possess properties affecting mast cell activities..."

5. "...Bloating is prevalent in gastroparesis and is severe in many individuals. Bloating severity relates to female gender, body weight, and intensity of other symptoms...Antiemetics, probiotics, and antidepressants with significant norepinephrine reuptake inhibitor activity may affect reports of bloating..."

6. "...This review focuses on the latest findings that support the therapeutic potential of GRLN-R agonists for the treatment of GI motility disorders. The review highlights the preclinical and clinical prokinetic effects of ghrelin and a series of novel ghrelin mimetics to exert prokinetic effects on the GI tract..."

7. "Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates hunger.[1] Ghrelin levels increase before meals and decrease after meals. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels..."

8. "...This novel data suggests that hyperlipidemia and/or suppression of selective antioxidants may be a potential cause of developing gastroparesis in diabetic patients."

9. "...This suggests that ghrelin would be an important player as a sensor of systemic oxidative stress"

10. This study reports that some chinese herbs improved symptoms.


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