The purpose of this site is to collect lab research by medical doctors about herbs that are proven to treat illnesses and counter the false attacks on herbs by the medical industry and false claims by alternative medicine. I let the science tell the facts.
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Thunder God Vine or lei gong teng a Chinese plant that has been used for ages in remedying a number of conditions including rheumatoid arthritis. The plant-derived agents triptolide and celastrol are from the "thunder god vine"

Side Effects and Cautions

  • Thunder god vine can cause severe side effects and can be poisonous if it is not carefully extracted from the skinned root. Other parts of the plant—including the leaves, flowers, and skin of the root—are highly poisonous and can cause death.
  • A number of participants in the NIAMS study experienced gastrointestinal adverse effects such as diarrhea, indigestion, and nausea, as well as upper respiratory tract infections. (The rate of adverse effects was similar in the thunder god vine and sulfasalazine groups.)
  • Thunder god vine can also cause hair loss, headache, menstrual changes, and skin rash.
  • There are no consistent, high-quality thunder god vine products being manufactured in the United States. Preparations of thunder god vine made outside the United States (for example, in China) can sometimes be obtained, but it is not possible to verify whether they are safe and effective.
  • Thunder god vine has been found to decrease bone mineral density in women who take the herb for 5 years or longer. This side effect may be of particular concern to women who have osteoporosis or are at risk for the condition.
  • Thunder god vine contains chemicals that might decrease male fertility by changing sperm.

The reports below indicate some great benifits of triptolide and celastrol which are extracted from the Thunder God Vine, however if it is not prepared properly its skin is highly poisonious. I could not find a safe source for it at this time.

1."A little-known plant with a truly bizarre name is now making headlines as a cancer killer, with the compound of the plant vanishing tumors in mice with pancreatic cancer. Known as the ‘thunder god vine’ or lei gong teng, the Chinese plant is actually integrated into Chinese medicine and has been used for ages in remedying a number of conditions including rheumatoid arthritis."

2. webmasters notes are in this color. "Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal malignancies (pancreatic cancer)..The plant-derived agent triptolide also known as "thunder god vine" has a long history in traditional Chinese medicine (TCM) for treatment of rheumatoid arthritis and cancer and is now in phase II trials...This study is the first to show that triptolide reverses EMT and CSC characteristics and therefore may be superior to current chemotherapeutics Chemo) for treatment of PDA." This report is full of scientific terms, but boiled down it is saying the component triptolide that is in the Thunder God Vine is better than chemo to treat prostate cancer.

3. "Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease...These data suggest that celastrol may serve as a potent agent for prevention of neurotoxin-induced neurodegeneration through multiple mechanisms and thus has therapeutic potential for the treatment of neurodegenerative diseases. Celastrol is another component from the Thunder God Vine and this report suggests it will treat neurodegenerative damage in Parkinsons disease.


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