"In India, the tree is variously known as "Sacred
Tree," "Heal All," "Nature's Drugstore,"
"Village Pharmacy" and "Panacea for all diseases."
Products made from neem tree have been used in India for
over two millennia for their medicinal properties: Neem
products have been observed to be anthelmintic, antifungal,
antidiabetic, antibacterial, antiviral, contraceptive and
sedative. Neem products are also used in selectively
controlling pests in plants. It is considered a major component
in Ayurvedic medicine and is particularly prescribed for
* All parts of the tree have medicinal properties (seeds,
leaves, flowers and bark) and are used for preparing many
different medical preparations.
* Part of the Neem tree can be used as a spermicide
* Neem oil is used for preparing cosmetics (soap, shampoo,
balms and creams, for example Margo soap), and is useful
for skin care such as acne treatment, and keeping skin elasticity.
Neem oil has been found to be an effective mosquito repellent.
* Neem derivatives neutralise nearly 500 pests worldwide,
including insects, mites, ticks, and nematodes, by affecting
their behaviour and physiology. Neem does not normally kill
pests right away, rather it repels them and affects their
growth. As neem products are cheap and non-toxic to higher
animals and most beneficial insects, they are well-suited
for pest control in rural areas.
* Besides its use in traditional Indian medicine, the neem
tree is of great importance for its anti-desertification
properties and possibly as a good carbon dioxide sink.
* Practitioners of traditional Indian medicine recommend
that patients suffering from chicken pox sleep on neem leaves.
* Neem gum is used as a bulking agent and for the preparation
of special purpose food (for diabetics).
* Aqueous extracts of neem leaves have demonstrated significant
* Traditionally, slender neem branches were chewed in order
to clean one's teeth. Neem twigs are still collected and
sold in markets for this use, and in India one often sees
youngsters in the streets chewing on neem twigs.
* A decoction prepared from neem roots is ingested to relieve
fever in traditional Indian medicine.
* Neem leaf paste is applied to the skin to treat acne,
and in a similar vein is used for measles and chicken pox
* Neem blossoms are used in Andhra Pradesh, Tamil Nadu and
Karnataka to prepare Ugadi pachhadi. "Bevina hoovina
gojju" (a type of curry prepared with neem blossoms)
is common in Karnataka throughout the year. Dried blossoms
are used when fresh blossoms are not available. In Tamilnadu,
a rasam (veppam poo rasam) made with neem blossoms is a
* A mixture of neem flowers and bella (jaggery or unrefined
brown sugar) is prepared and offered to friends and relatives,
symbolic of sweet and bitter events in the upcoming new
Extract of neem leaves is thought to be helpful as malaria
prophylaxis despite the fact that no comprehensive clinical
studies are yet available. In several cases, private initiatives
in Senegal were successful in preventing malaria. However,
major NGOs such as USAID are not supposed to use neem tree
extracts unless the medical benefit has been proved with
clinical studies." http://en.wikipedia.org/wiki/Azadirachta_indica
May treat depression and
mental conditions. "Deoxygedunin, a
natural product with potent neurotrophic activity in mice.Jang
SW, Liu X, Chan CB, France SA, Sayeed I, Tang W, Lin X,
Xiao G, Andero R, Chang Q, Ressler KJ, Ye K.Department of
Pathology and Laboratory Medicine, Emory University School
of Medicine, Atlanta, Georgia, USA.
Gedunin, a family of natural products from the Indian neem
tree, possess a variety of biological activities. Here we
report the discovery of deoxygedunin, which activates the
mouse TrkB receptor and its downstream signaling cascades.
Deoxygedunin is orally available and activates TrkB in mouse
brain in a BDNF-independent way. Strikingly, it prevents
the degeneration of vestibular ganglion in BDNF -/- pups.
Moreover, deoxygedunin robustly protects rat neurons from
cell death in a TrkB-dependent manner. Further, administration
of deoxygedunin into mice displays potent neuroprotective,
anti-depressant and learning enhancement effects, all of
which are mediated by the TrkB receptor. Hence, deoxygedunin
imitates BDNF's biological activities through activating
TrkB, providing a powerful therapeutic tool
for treatment of various neurological diseases."
" These results suggest a new approach in
cancer immunotherapy by modulating dysregulated
CCR5 signals from MO/Mphi.Cellular & Molecular Immunology
advance online publication,...PMID: